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[DOI] [Google Scholar] 163.Hernndez-Alcntara A.M., Totosaus A., Prez-Chabela M.L

Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreichs ataxia YG8R mouse model

As for UGT74F2, while each individual mutation (T365A or T15S) did not significantly affect the activity, compared to the wild-type UGT74F2, the double mutant UGT74F2 T15S, T365A displayed an 85% decrease in activity for SGE production (Fig