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Potency loss accelerates rapidly, and contamination risk increases

10.1007/s13361-019-02288-2 148 DonaldsonL.CaponeJ

Unfortunately, and ironically with the latest FDA restriction: Only large well-funded companies can afford FDA trials Naturally occurring peptides are hard to patent No patent = no financial incentive No incentive = no approval No approval = no legal compounding Thats the present reality, I hope this regulatory and political standstill will resolved in the coming years

214 For example, the antibacterial and antiviral capabilities of AMPs make it difficult to use the commonly used bacteria and viruses as expression systems