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Several SNPs located in the genes for cystathionine -ligase (CTH), alcohol dehydrogenase 5, GCL and glutaredoxin showed significant or suggestive associations with autism spectrum disorders

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Due to its function in maintaining CNS metal homeostasis and the established link between metal dyshomeostasis and neurodegenerative diseases 6,7,21,22 , MT3 represents an important target for investigation in ALS and MS