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for example, isoniazid, cycloserine, penicillamine, and hydralazine each form complexes with B or otherwise interfere with B metabolism, potentially leading to deficiency and peripheral neuropathy

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People who have undergone some sort of trauma to the intestines including a gastric bypass or intestinal surgery can be susceptible to vitamin B12 deficiencies since they may have less cells present to produce the protein to which the B12 can attach, resulting in a decreased ability to absorb B12 into the bloodstream