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doi: 10.1186/s12889-018-5526-2

The skin predominantly contains -, -, -carotene lutein, zeaxanthin, lycopene, and their isomers as the main forms of carotenoids ( Carotenoids are also utilized in dermatological and cosmetic products as active ingredients for skin application ( In vitro and in vivo tests have revealed the effects of carotenoids on patients with AD ( Some studies highlighted the role of vitamin A deficiency in the pathophysiology of AD, especially in early childhood

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By correcting cellular dysfunction often seen with aging, zinc supplementation may help delay the onset and progression of conditions such as age-related macular degeneration [20], diabetes mellitus [21], wound-healing impairments [22], depression [23] and cardiovascular disease [24], ultimately improving health outcomes for older adults