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With that, these results provide valuable insights into the impact of amyloid-like structures on NPCs phenotypes and behaviors, presenting a promising scaffold for future investigations into AD mechanisms and drug testing

Diagnostics include but are not limited to the following: Muscle enzymes for complaints of muscle pain Calcium, vitamin D and parathyroid hormone levels in the presence of bone pain or fragility Liver enzymes if the physician suspects liver damage Blood lipids and glucose for at-risk patients Pancreatic enzymes for possible pancreatitis Complete blood count and clotting function tests to look for blood problems A mild blood test abnormality may be addressed by lowering the dose and continuation of monitoring

Data have been disaggregated by sex where available and appropriate, and individual-level sex-disaggregated data are included in the Source Data file

Thermosensitive liposomes ( 51a &CAT@TSL) containing 51a (called also IR-820