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Understanding Vitamin B12 and Iron: Essential Nutrients for Health Vitamin B12 and Iron are key for our health

The investigator, in consultation with the IRB/EC, may pause or terminate the study if SAE rates are unexpectedly high or if new information changes the risk-benefit profile

The main analysis will be supplemented with a multivariate linear regression to adjust for potential confounding variables (age, gender, baseline erosion area, periodontitis stage, baseline VAS score, smoking history, systemic medical history, and concomitant medications), and a repeated-measures mixed-effects model will assess the dynamic effect of the intervention