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As a result, when ROS levels rise due to chronic ethanol exposure, neurons are at a heightened risk for oxidative damage

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In the present study, we have, therefore, utilized these unique samples and applied an optimized triple-label immunohistochemical protocol for comparing the localization of GPX1 in beta and alpha cells and for estimating its level and relative expression in the two cell-types in high-quality human pancreatic sections from diabetic and non-diabetic deceased donors, supplied by the Network for Pancreatic Organ Donors with Diabetes (nPOD) and the Exeter Archival Diabetes Biobank (EADB) (Morgan and Richardson 2018

In individuals with melasma, keratinocytes experience an increased production of ARG2, resulting in the buildup of melanosomes within these cells