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In 5xFAD mice, selective neuronal loss is found in cortical layer 5 (L5), without affecting the overall neuron number in the total frontal cortex and hippocampus, and this correlates with the reduced anxiety-like behavior (Jawhar et al., 2012)

Considering the above, it was not possible to identify clinical trials that clarified the effective use of lithium in BD I and BD II, nor trials that specifically evaluated or differentiated efficacy and doses between the acute and maintenance phases

[15] Ligneous conjunctivitis, resolving after discontinuation of therapy, also has been reported in patients taking oral tranexamic acid

Necroptosis and inflammation