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Yet another compound, Honokiol (HKL), has been shown to protect against doxorubicin-induced cardiotoxicity by activating SIRT3, which helps reduce ROS production, prevent mitochondrial fragmentation, and promote mitochondrial fusion 187

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Safety: Its important to note that while AOD-9604 demonstrated excellent safety and tolerability, the clinical development program was ultimately discontinued because efficacy for weight loss did not meet regulatory approval standards

Theyre incredibly effective at managing weight and Type 2 diabetes