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Thus, UA promotes autophagic cell death and triggers ferroptosis, establishing it as a promising therapeutic agent in cancer treatment

In response, plants activate nutrient transporters (ZIP, NRAMP, HKT, PHT), synthesize chelators (phytosiderophores), and exude organic acids to improve nutrient acquisition and redistribution

[DOI] [PubMed] [Google Scholar] 35.DHaens G, Lemmens L, Geboes K, Vandeputte L, Van Acker F, Mortelmans L, Peeters M, Vermeire S, Penninckx F, Nevens F, et al

Inflammatory factors and oxidative stress damage the intestinal mucosal barrier, leading to reduced expression and impaired function of tight junction proteins, as well as increased intestinal permeability