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10.3390/ijms17050631 35 LuoW.BrouwerC

Lipid metabolism refers to a series of biochemical processes involving uptake, synthesis, lipolysis, storage, oxidation, and metabolic reprogramming, which form the basis of energy storage and supply and play indispensable roles in cell membrane architecture, hormone biosynthesis, immune modulation, neural function, and thermoregulation [6]

When elevated, sustaining a 25(OH)D 3 level of 50 ng/mL (requires about 4000 IUs/day) becomes difficult, as these divalent cations compete for the same receptor