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The evidence base for their use in weight management is very limited, and the MHRA has previously issued safety warnings about unlicensed injectable preparations of this type

A multiple imputation approach was used to handle missing data 31 , with imputation based on available data from participants in the same treatment arm with the same treatment status (on-treatment or discontinued)

Now Im not talking below average B12, or suboptimal B12 levels, or even whats clinically called B12 depletion, where your levels place you at high risk for deficiencybut actual bonafide vitamin deficiency, meaning that your levels are so low your biochemistry is screwed up

Week by week expectations Understanding typical progression helps set realistic expectations and identify whether your protocol needs adjustment