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Nov 2019;64(11):747-760

In vivo, bilateral ICI of PRDX2ADSCs in a BCNI model in SpragueDawley rats resulted in superior erectile function, reduced corporal fibrosis, increased smooth muscle content, and attenuated oxidative stress and ferroptosis within the corpus cavernosum [81]

ROS may be implicated in the regulation and responsiveness of stress sensors by enhancing the antioxidant defense via p53 to maintain cellular redox balance and by indirectly modulating selective transactivation of p53 target genes [35]