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The PANTHER GO-Slim analyses revealed an association of HPX with the biological processes that fall into the following groups: hemostasis, regulation of response to wounding, activation of immune response, complement activation, coagulation, regulation of metal iron ion transport, and regulation of body fluid levels ( i.e ., kidney function)

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IGF-1 LR3 functions through direct, sustained agonism of the IGF-1 receptor (IGF-1R), a receptor tyrosine kinase, activating the same downstream intracellular signalling cascades as native IGF-1 but with substantially reduced IGFBP-mediated attenuation and a far longer biological activity window

Complementarity and redundancy of IL-22-producing innate lymphoid cells