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doi: 10.1023/b:caco.0000007962.19066.9c 108 KolodziejczykA

Individuals taking metformin alongside Mounjaro face increased risk of B12 deficiency, as metformin is known to impair B12 absorption, and may require more frequent monitoring

MOTS-c is the other common pairing in laboratory work on energy metabolism, since it acts on mitochondrial pathways and insulin sensitivity rather than on adrenergic receptors