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7 Department of Medical Genetics, King Faisal Specialist Hospital & Research Center, 8 The National Newborn Screening Program, Ministry of Health, Riyadh, Saudi Arabia

(PubMed) Caldwell KL, Makhmudov A, Ely E, Jones RL, Wang RY

MACE: major adverse cardiovascular events

Treatment with HU and LC reduces frequency of blood transfusions, in hospital days, and number of painful episodes per year, as such it cuts the economic burden of SCA in a given society