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Description

It is widely used in early pharmacology research and is endorsed in dose conversion literature (Nair & Jacob, 2016)

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Although emerging therapies such as glucagon-like peptide-1 (GLP-1) analogues (e.g., semaglutide) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists (e.g., tirzepatide) have received clinical approval for obesity management, substantial demand persists for alternative or adjunctive therapies employing distinct mechanisms