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Genetic Variability of Human Diamine Oxidase: Occurrence of Three Nonsynonymous Polymorphisms and Study of Their Effect on Serum Enzyme Activity. Pharmacogenetics and Genomics, vol

However, researchers must account for potential variability in absorption

You may need B12 injections if you: Have been diagnosed with pernicious anemia Have gastrointestinal issues (e.g., Crohns disease, celiac disease, or after bariatric surgery) Follow a strict vegan or vegetarian diet without adequate supplementation Are over the age of 50, as absorption decreases with age Take certain medications that interfere with B12 absorption Have chronic fatigue, memory issues, or nerve problems due to B12 deficiency

and June 9, 2017.