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Hama Aziz et al., 2023)

Yang N, Gong F, Liu B, Hao Y, Chao Y, Lei H, Yang X, Gong Y, Wang X, Liu Z

This is an inherited genetic disease called pyroglutamic aciduria which manifests as hemolytic anemia and metabolic acidosis, causing neurological disorders and vulnerability to bacterial infections, and which can be classified as mild, moderate or severe depending on the severity of the symptoms

It serves as an essential cofactor for enzymes involved in neurotransmitter synthesis, including tyrosine hydroxylase for dopamine production and tryptophan hydroxylase for serotonin synthesis [12]