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The 2026 Medicare rate is $109.55 to $131 in non-facility settings depending on GPCI locality

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This axis is anatomically and functionally mediated by autonomic pathways (sympathetic/parasympathetic regulation of cardiovascular function), humoral factors (e.g., hormones, cytokines), and afferent signaling from cardiac receptors to brainstem and limbic regions, integrating neural, endocrine, and sensory crosstalk