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Tell your prescribing doctor if you have any of these conditions, which can increase B12 shot side effects: An allergy to cobalt Kidney disease Severe megaloblastic anemia Side Effects from B12 Shots The most common B12 shot side effect is swelling at the injection site

you will not use them in or on humans or animals

This is also where the supply-versus-stability point from the reconstitution section bites: if a reconstituted 10 mg vial holds ~66 doses but the solution is only reliably stable for a few weeks, plan the reconstitution volume so you are not left discarding drug you paid for

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