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The clinical translation of mitophagy in ischemic heart disease still needs to be further strengthened

Analyzing the recent industrial movements reveals a trend toward consolidation and massive scale-up to meet projected future demand

Resulted homogenate was centrifuged 4000 g/15 min at 4 C and the amount of proteins was assessed with BCA kit (Thermo Fisher Scientific, #23225) in supernatant containing cytosolic fraction

Although we used a mild STZ-induced diabetic mouse model that mimics certain aspects of type 2 diabetes, the inclusion of additional insulin-resistant or diet-induced models in future studies could enhance generalizability