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176 Mitochondria tagged with phosphorylated poly-Ub chains by Parkin are recognized by ubiquitin-binding receptor proteins such as OPTN, NDP52, SQSTM1/p62, TAX1BP1, and NBR1, 177,178,179 which then bind with LC3 to initiate mitophagy

Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease

C22-sterol desaturase was the only DEG in sterol metabolism pathway, and its expression was decreased by 0.3-fold induced by MT treatment, indicating that MT could inhibit the sterol metabolism pathway which was a competing pathway with the astaxanthin synthesis to improve astaxanthin production