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When the tumor size reached 6 mm in diameter, different formulations including (i) PBS, (ii) siPlk1 alone, (iii) siPlk1/ADC-CS and (iv) siPlk1/Ap-CS were separately administrated intravenously at a dose of 100 L of siRNA (the siRNA concentration is 0.91 M) per animal every other day

5 Subsequently, the pathogenic role of ferroptosis in the progression of I/R-induced acute damage in the lungs, heart, and intestinal tract has been validated in animal models

doi: 10.1016/j.foodchem.2024.138645 48 MobasheriFKhajehMGhaffari-MoghaddamMPiriJBohlooliM