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ElShunnar SK, Hoare DJ, Smith S, et al

Mitochondria and apoptosis

This study evaluates curcumin's neuroprotective potential against arsenic trioxide (As 2 O 3 ) in the mouse striatal region

These approaches include the combined use of STING agonists, Nrf2 inhibitors, lactate metabolism blockers, and mitoNIDs, which collectively alleviate immunosuppressive metabolic states, restore T cell function [89,90,91], and improve the responsiveness of MSS CRC to immune ICIs