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Fermentation 3, 117

Laboratory studies have also examined its proposed role in modulating gene expression, circadian and pineal regulatory pathways, oxidative-stress responses, and the development of spontaneous tumors in rodent models

In this regard, based on the complex scenario depicted by evidence from the literature discussed above, we applied a model-based network approach for the Homo Sapiens proteome recapitulating the mechanistic connection between the molecular clock and the biological pathways herein investigated (Fig