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The harmful chemicals in smoking directly damage lung cells, causing DNA mutations that increase cancer risk. Over time, these damaged cells grow abnormally, leading to tumor formation in the lungs. Quitting smoking Tobacco carcinogens, their biomarkers and tobacco induced cancer Nature Reviews Cancer Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention Nature Reviews Cancer What chemicals are in a cigarette? What does smoking do to your body? Cancer Research UK
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