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JAK/STAT signaling as a key regulator of ferroptosis: mechanisms and therapeutic potentials in cancer and diseases

Glutathione (GSH) is recognized as the most important antioxidant produced in the human body

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By analyzing the common characteristic changes during DTP transformation, such as cell-cycle restriction, embryonic-like diapause, stem-like phenotype, and reversibility of transformation, it is clearly recognized that cancer cell transformation into DTP cells poses a significant challenge in anticancer therapy