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The total drug does not change

Furthermore, this study showed that at the same concentration, the efficacy remained stable over time, as the percentage of dead bacterial cells at the highest DJK-5 concentration (10 g/mL, 6.5 M) was similar between 1 day (8591%) and 3 days (8791%) in all biofilms of the three donors and in all cases [28]

For instance, about a 400-fold increase over baseline was retained in the isolated stratum corneum

For a non-gut issue like sciatica, injectable administration is the standard for research to ensure sufficient levels of the peptide reach the target tissues and enter circulation