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Both medicines are unlicensed in the UK, meaning they cannot be prescribed through standard NHS or private prescribing routes

18 Other studies of high quality (randomized placebo-controlled trials) have noted benefit with these same doses with regards to measurements of Parkinsons disease severity such as the Unified Parkinsons Disease Scale Rating (UPDRS) which assess mentation, behavior, mood, activities of daily living, and motor skills among other areas impacted by Parkinsons disease

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These substrates include lipid metabolism disorders, elevated blood pressure, chronic inflammation, cardiac structural remodeling, and electrophysiological abnormalities (Lavie et al., 2017