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Am J Dis Child 1991;145:999-1001

A number of studies have indicated that, as compared with mammals, the responses of the activities of many glucose metabolism-related key enzymes, such as GK, PFK and PK, are not sensitive to the increased dietary carbohydrate content in fish 36,37

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In muscle tissue, studies have found reduced myofiber diameter and modifications in gene expression associated with muscle growth, atrophy, and repair, such as upregulation of atrogin-1, calpain and caspase genes, further supporting evidence of both structural and metabolic injury due to microplastics [147]