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The -cell in diabetes: from molecular genetics to clinical research

While FDG-PET (fluorodeoxyglucose positron emission tomography) has long been the clinical standard for imaging glucose metabolism, several emerging techniques promise to provide more comprehensive metabolic information: Hyperpolarized MRI: This technique dramatically enhances the sensitivity of magnetic resonance spectroscopy, enabling real-time measurement of metabolic flux

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For purification, a 5 ml GSTrap FF (GE Healthcare) was equilibrated with at least five column volumes of reducing lysis buffer