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These evidences support the notion that cancer cells could avoid oxidative stress-induced ferroptosis through activating the SIRT2-GCLC-GSH signaling axis

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While this primarily affects the GH axis, the pituitary is a complex gland responsible for producing many hormones (LH, FSH, TSH, etc.)

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Therefore, although the data from these studies are promising, applying them directly to human IRI cases is premature

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