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10.1126/science.1090389 Science 246 Wislet-GendebienS.VisanjiN

In addition, the release of damage-associated molecular patterns by tumor cells undergoing ferroptosis also mediates antitumor immunity, and immune therapy can synergize with targeted therapy or radiotherapy through ferroptosis

-glutamyltranspeptidase cleaves glutathione at the unique -glutamyl bond to form free glutamate and the dipeptide Cys-Gly, which is degraded to Cys and Gly for transport in to cells via amino acid transporters

[109] Melatonin is also known to modify many cytokines, including TNF, IL1, IL-2, IL-6, and gamma-interferon, in ways consistent with increased host defense against cancers