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These differences were not related to lithium exposure [37], suggesting that mitochondrial abnormalities are not caused by BD treatment

In contrast, prolactin levels within the physiological range, particularly the proposed HomeoFIT-PRL range (approximately 7100 g/L), are associated with more favorable metabolic indicators

The resultant accumulation of reactive oxygen species within erythrocytes leads to oxidation of hemoglobin (methemoglobin) and accumulation of denatured hemoglobin, which can result in hemolytic anemia, reduced arterial oxygen saturation on pulse oximetry, and impaired oxygen delivery to tissues from methemoglobin, often necessitating supplemental oxygen

VRK2 protects PC cells from ferroptosis by facilitating SLC7A11 trafficking Since SLC7A11-mediated cystine uptake and subsequent biosynthesis of GSH detoxifies phospholipid peroxidation and protects cells from ferroptosis [26], we speculated that VRK2-deficient PC cells, vulnerable to GSH inhibition is associated with ferroptosis