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Oxidative stress mediated by the JNK/p53 signalling pathway leads to ferroptosis

Accuracy: Eliminate common errors from manual conversions

This is in line with our previous findings [36] that demonstrated that CDK4/6 inhibition primarily directs glutamine towards -ketoglutarate (-KG) production to replenish the TCA cycle

21 Oral administration may be beneficial for patients with preclinical toxic effects or hepatic injury, although the presence of altered mental status and vomiting may limit its use