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A spontaneous inherited predisposition for hepatic iron pigmentation has been reported in Sprague-Dawley rats (Masson and Roome 1997), and iron deposition can be found in the aging mouse liver (Harada et al

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The implication of EVs as biomarkers for different diseases makes their detection crucial for early diagnosis and monitoring of diseases (Simons and Raposo, 2009)

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Currently, isolated RNA can be used to evaluate both mRNA and microRNA (miRNA) (Lizarraga et al

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