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In addition, increasing evidence highlights their noncanonical anti-inflammatory properties, as well as other nonimmune functions, including the promotion of adipose tissue browning and the enhancement of angiogenesis through extracellular HSP70 activity

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3.4 Viral vectors Viral vectors serve as a type of delivery system that possesses natural transmembrane transport capabilities, and they have demonstrated potentials in achieving brain-targeted drug delivery across BBB by emulating the natural infection mechanisms of viruses (He et al., 2025