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There is abundant evidence that oxidant stress may play an important role in the modification of vascular thromboresistance in moderate hyperhomocysteinemia

ABSTRACT The mechanisms of antioxidant action of lactic acid bacteria (LAB) have not been fully explained

The reduced thiol group on the cysteine residue directly scavenges reactive oxygen species (ROS) and reactive nitrogen species (RNS), becoming oxidized to GSSG in the process

This holistic perspective is critical for the development of multi-targeted therapeutic strategies, as single-pathway interventions are unlikely to address the multifactorial nature of the disease