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Despite growing interest in algal phycoremediation, species differ markedly in their tolerance, uptake behavior, and biochemical defense capacity under metal stress

447,448,449,450 Upregulated autophagy in macrophages enhances the production of pro-inflammatory cytokines such as IL-6 and TNF-, while autophagy deficiency promotes exaggerated inflammasome activation, as demonstrated by ATG16L1 ablation increasing IL-1 and IL-18 secretion

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