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TALEN-mediated gene editing method for GRK5-KO mice

However, the role of epigenetic regulation in endothelial cell function has only recently begun to be explored in detail [9]

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In addition, a study showed that 5-azacitidine can significantly increase the tri-methylation of lysine-4 on histone H3 in mouse primary spermatocytes, which indicated that 5-azacitidine could modulate histone methylation (Burlibaa et al., 2021)