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Gold nanoparticles alter parameters of oxidative stress and energy metabolism in organs of adult rats

To examine the role of Vs in the intracellular reduction of H 2 O 2 through GPX activity, we exploited Orp1roGFP2 and Grx1roGFP2 biosensors that allow noninvasive imaging of the intracellular H 2 O 2 and E GSH , respectively (Gutscher et al, 2008