why does l carnitine make you smell fishy Deficiency: What Is It, Causes, Symptoms, and More Trimethylamine - Wikipedia

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Some other animated efforts that came out around the same time, like Brother Bear (2003), Home on the Range (2004), The Polar Express (2004), Shark Tale (2004), Robots (2005) and Valiant (2005), while perfectly acceptable animated efforts in their own right, ended up being dismissed as banal and found mixed success

The substitution of one of the oxygen atoms in the phosphate group with sulfur is the modification that makes the aptamer resistant to nuclease degradation (136)

doi: 10.1126/science.72.1855.76