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neoformans employs multi-layered antioxidant mechanisms, including upregulating superoxide dismutase, glutathione systems, and melanin synthesis to neutralize ROS, while utilizing inositol metabolism to maintain membrane integrity and evade immune recognition (Spadari et al., 2018) (Figure 2)

The associated increase in LLF glutathione can protect lung airway epithelial cells against oxidant injury associated with inflammation in asthma

Pachman DR, Qin R, Seisler DK, Smith EM, Beutler AS, Ta LE, et al

And where lifestyle alone may not be enough, we can support the system : with precursors like NAC and glycine and, in modern settings, with clinical delivery methods that restore what diabetes so often drains