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Description

Limited half-life and stability Liposomes for their limited half-life and susceptibility to degradation and fusion present significant challenges in drug delivery

doi: 10.1038/nature07383

The CGI-Improvement scale (CGI-I) was used to evaluate the degree of improvement in the patients symptoms relative to the baseline, and the CGI-Efficacy Index (CGI-EI) assessed the clinical efficacy of bumetanide by considering both the treatment effect and associated side effects