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B12 supplements can interact with certain medicines, including: Chloramphenicol (Chloromycetin Sodium Succinate) Proton pump inhibitors Metformin (Glucophage, Glumetza, Riomet) Gastric acid inhibitors If youre taking any of these medications, talk to your doctor or pharmacist before starting a B12 supplement

Lower NNMT cuts the shift of nicotinic acid (NA) to 1-methylnicotinamide (1-MNA)

Yen, a family doctor at Liansin Clinic in Taipei, told CNA that the recommended daily intake of vitamin B12 for people over 14 years old is 2.4 micrograms

doi: 10.3389/fendo.2024.1426103 Received 30 April 2024 Accepted 11 November 2024 Published 05 December 2024 Volume 15 - 2024 Edited by Stanisaw Surma, Medical University of Silesia, Poland Reviewed by Celeste Annemarie De Jager Loots, Imperial College London, United Kingdom Omar A