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confirmed that overexpressed SLC1A3 in gastric cancer activates the PI3K/AKT pathway, upregulates the expression levels of Glucose transporter 1 (GLUT1), Hexokinase 2 (HK2), and Lactate dehydrogenase A (LDHA), and promotes the growth of gastric cancer, while treatment with the PI3K/AKT inhibitor LY294002 could inhibit the growth-promoting effect of SLC1A3 overexpression on gastric cancer

Chem Res Toxicol 30:162176

Isocitrate dehydrogenase may be the primary source of NADPH in the cytosol

Coated MNs enable biomarker detection in ISF through surface modification with conductive and catalytic materials, serving as the most widely employed working electrodes (WE) in electrochemical MN sensors