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The peptide has also shown preliminary interest in cartilage and joint research

For instance, treatments with apple polysaccharides, flos lanicera, and Bofutsushosanan herbal remedy from Japanhave been successful in promoting the growth of beneficial bacteria like Lactobacillus and Bacteroidetes , improving intestinal barrier integrity, and decreasing pro-inflammatory cytokines such as TNF- and IL-6 [117,118,119]

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Renal failure is, therefore, an end result of the muscle damage and may be severe enough to require hemodialysis to prevent death from uremia