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Despite the fact that the technique concurs to the treatment of a relatively extended region of hypopigmentation rapidly, a split-thickness skin graft has some disadvantages, as well as an insufficient color and texture correspondence between the treated and donor area: disturbance of sensation within the recipient area could develop displacement of the grafts, milia formation, perigraft depigmentation, and imperfect scarring at recipient or donor areas [128,129]

The answer depends on dosing, timing, and your individual metabolic profile, which PlexusDx can help clarify through genetic testing and clinical monitoring

Evening dosing (30 to 60 minutes before sleep) is strongly recommended so that nausea and flushing peak during sleep rather than during the day

Skeletal Radiol (2016) 45:2934